Cerene Biomedics http://cerenebiomedics.com Wed, 10 Jun 2009 06:41:06 +0000 http://wordpress.org/?v=2.7.1 en hourly 1 Contact Us http://cerenebiomedics.com/contact-us/ http://cerenebiomedics.com/contact-us/#comments Sat, 04 Apr 2009 03:21:27 +0000 admin http://cerenebiomedics.com/?p=41 email us at: info@cerenebiomedics.com

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]]> http://cerenebiomedics.com/contact-us/feed/ Team | Our Story http://cerenebiomedics.com/team/ http://cerenebiomedics.com/team/#comments Sat, 04 Apr 2009 03:08:32 +0000 admin http://cerenebiomedics.com/?p=33 We met during graduate school while pursuing degrees in biomedical engineering at Duke University. Our collective interest in medical devices and entrepreneurship brought us together to form a team to develop an implantable cooling device to treat epilepsy.  This exciting opportunity led us to compete in several national business plan competitions and provided us with invaluable guidance as well as initial non-dilutive funding to start product development.


Our team is comprised of:

Christina Li - Doctoral candidate in Biomedical Engineering at Duke University.

Heidi Koschwanez - PhD in Biomedical Engineering from Duke University (matriculated 2009).

John Stroncek - Doctoral student in Biomedical Engineering at Duke University.

Carolyn Nohejl - Dual Masters degree student in Biomedical Engineering and Business Administration at Duke University.

]]> http://cerenebiomedics.com/team/feed/ Press http://cerenebiomedics.com/press/ http://cerenebiomedics.com/press/#comments Sat, 04 Apr 2009 02:35:06 +0000 admin http://cerenebiomedics.com/?p=28
  • Fuqua School of Business - 02.26.09
    Connecting Disciplines: Living Room Becomes Lab for New Venture
  • Reuters | SEBIO - 12.17.08
    Cerene Biomedics winner of the 2nd annual BIO/Plan Competition
  • Fuqua School of Business - 09.11.08
    Getting Down to Business
    • ]]>
  • Fuqua School of Business - 02.26.09
    Connecting Disciplines: Living Room Becomes Lab for New Venture
  • Reuters | SEBIO - 12.17.08
    Cerene Biomedics winner of the 2nd annual BIO/Plan Competition
  • Fuqua School of Business - 09.11.08
    Getting Down to Business
  • Pratt Engineering Duke University - 09.09.08
    Freezing the Epileptic Brain
  • Pratt Engineering Duke University - 06.06.08
    Students’ Plan to Tackle Epileptic Seizures
  • University of Maryland - 05.09.08
    Cerene wins Business Plan Competition
  • CNN Money - 05.02.08
    Student grudge match - A new way to halt seizures
  • Duke Start-Up Challenge - 04.21.08
    Cerene takes 1st place overall
    • ]]>     http://cerenebiomedics.com/press/feed/     Careers http://cerenebiomedics.com/careers/ http://cerenebiomedics.com/careers/#comments Sat, 04 Apr 2009 02:27:19 +0000 admin http://cerenebiomedics.com/?p=23 We are always looking for new innovative and enthusiastic people.   Please email us for our career opportunities.

    info@cerenebiomedics.com










    ]]>     http://cerenebiomedics.com/careers/feed/     Company Overview http://cerenebiomedics.com/company-overview/ http://cerenebiomedics.com/company-overview/#comments Fri, 03 Apr 2009 23:05:48 +0000 admin http://cerenebiomedics.com/?p=15 Epilepsy is a chronic neurological disorder that can affect people of all ages across the globe. Epilepsy and seizures affect over 3 million Americans. Unfortunately 30% of patients with epilepsy do not respond adequately to current treatments. Cerene Biomedics is developing an implantable medical device to help this refractory population stop epileptic seizures by cooling the surface of the brain. Brain cooling has been shown to be a safe and effective means to stop seizures when applied locally to the seizure focus. This device will provide first line therapy for epilepsy patients with a seizure focus on the neocortex. ]]> Cerene Biomedics is an early stage start-up focusing on developing a new cooling therapy to treat patients suffering from epilepsy.  Approximately three million Americans have epilepsy; 200,000 new cases are diagnosed annually in the United States alone . Although anti-convulsants have been used to control the disease and reduce the severity and occurrence of seizures, one-third of individuals with epilepsy do not adequately respond to medication or may experience severe side effects.  Recent research shows targeted cooling to the surface of the brain reduces seizures in patients refractory to conventional therapy and has been shown to be safe in long term studies.


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    Epilepsy Facts¹:

    • Epilepsy and seizures affect over 3 million Americans of all ages, at an estimated annual cost of $15.5 billion in direct and indirect costs.
    • Approximately 200,000 new cases of seizures and epilepsy occur each year.
    • Ten percent of the American population will experience a seizure in their lifetime.
    • Three percent will develop epilepsy by age 75.



    ¹Epilepsyfoundation.org

    ]]>     http://cerenebiomedics.com/company-overview/feed/     Technology http://cerenebiomedics.com/technology/ http://cerenebiomedics.com/technology/#comments Thu, 02 Apr 2009 03:12:04 +0000 admin http://cerenebiomedics.com/?p=35 Cerene Biomedics is in early stages of product development.  Below are selected peer-reviewed references to support the safety and efficacy of cooling.


    References

    1 Yang XF, Kennedy BR, Lomber SG, Schmidt RE, Rothman SM. Cooling produces minimal neuropathology in neocortex and hippocampus. Neurobiology of Disease. 2006 Sep;23(3):637-643.
    2 Schmitt FC, Buchheim K, Meierkord H, Holtkamp M. Anticonvulsant properties of hypothermia in experimental status epilepticus. Neurobiology of Disease. 2006 Sep;23(3): 689-696.
    3 Rothman SM, Smyth MD, Yang XF, Peterson GP. Focal cooling for epilepsy: An alternative therapy that might actually work. Epilepsy & Behavior 2005 Sep;7(2):214-221.
    4 Bakken HE, Kawasaki H, Oya H, Greenlee JD, Howard MA 3rd. A device for cooling localized regions of human cerebral cortex. J Neurosurg. 2003 Sep;99(3):604-608.
    5 Karkar KM, Garcia PA, Bateman LM, Smyth MD, Barbaro NM, Berger M. Focal cooling suppresses spontaneous epileptiform activity without changing the cortical motor threshold. Epilepsia. 2002 Aug;43(8):932-935.
    6 Lomber SG, Payne BR,  Horel JA. The cryoloop: an adaptable reversible cooling deactivation method for behavioral or electrophysiological assessment of neural function. Journal of Neuroscience Methods. 1999 Jan;86(2): 179-194.
    7 Sartorius CJ, Berger MS. Rapid termination of intraoperative stimulation-evoked seizures with application of cold Ringer’s lactate to the cortex. J Neurosurg. 1998 Feb;88(2):349-351.
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